Welcome to Alinea Clinical Research

About Us

Why Alinea


At Alinea, you will soon discover one simple concept, we genuinely care. We pride ourselves in quality clinical research; therefore, we deliver quality data to our sponsors and quality care to our patients.

About Alinea


Alinea Clinical Research has 2 integrated sites in North Texas.  Our Grapevine site is conveniently located 10 minutes from DFW airport. Our Denton site is conveniently located 2 minutes off highway 35N . We perform phases I-IV clinical trials for multiple indications. Dr. Kotsanis oversees all trials as the Principal Investigator (study doctor) and has over 25 years of experience in clinical research.  Dr. Kotsanis and Alinea Clinical Research staff work together with the same passion of bringing new and improved therapies and investigational drugs and devices to market.   Our passion is to make a difference each and every day and to leave a positive footprint in the world.

Areas of expertise


We are experienced in the following indications:

  • Autism
  • GI issues
  • Migraine/headaches
  • Osteoarthritis
  • Autoimmune Diseases
  • Immunodeficiency Diseases
  • Cancer
  • COPD and asthma
  • Dermatology
  • Allergies
  • Chronic Infection
  • Pain
  • Hypertension
  • Cholesterol
  • Alzheimer's & Parkinson's Disease


In this interview by Fox 26 Houston, Dr. Ginsberg explains the Parkinson's & MS clinical trial currently conducted in Houston.  We will be conducting an Alzheimer's study using young fresh frozen plasma within the next couple months.  Please contact us for details!


Dr. Ginsberg provides an update on one month study  results from the ongoing Parkinson's & MS study currently conducted in Houston, TX.  We are hopeful patients will continue to see improvement from young fresh frozen plasma infusions!


Are you interested in participating in any of our clinical trials? Subscribe to our mailing list to receive information on current and upcoming studies.

Our Lead Staff


Constantine Kotsanis, MD, PI

Dr. Kotsanis is a board-certified otolaryngologist (ENT).  Originally from
Greece, he settled in Chicago with his family when he was 15 eager to experience the American Dream .  He returned to Greece for medical school at the University of Athens, then continued his specialty trainig in otolaryngology, head and neck surgery at Loyola University at Chicago, which was where he met and married his wife, Beverly.  After finishing residency in Chicago, Dr. Kotsanis and his wife moved to Texas in 1983 and opened his practice.  Dr. Kotsanis has been conducting research for over 20 years and he continues to write protocols for cancer studies in his practice.    


Vanessa Galvan, MA, CRC

Vanessa founded Alinea Clinical Research in early 2018 and is the Site Director, but also conducts studies as the Lead Coordinator.  Vanessa's research journey started in 2007 in Omaha, NE where she conducted Phase 1-4 studies.  After moving to Dallas in 2009 with her husband and daughters, she continued her research career as a Senior Site Director for one of the largest Site Management Organizations in the country.  She has a passion for cancer research, but enjoys the challenge of learning new indications.  Vanessa continues to work with Dr. Kotsanis and his team to construct new study protocols and grow the research department. 

Elizabeth Seymour, MD, PI


Alinea Overview Sheet (pdf)


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Alinea Clinical Research

2260 Pool Road, Grapevine, Texas 76051, United States




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