About Us

Who We Are


Alinea Clinical Research is an integrated site located within the Kotsanis Institute in Grapevine, Texas and we also have two additional satellite clinics in Denton and Dallas, Texas. At Alinea, our patients and sponsors are more than just numbers to us. We genuinely respect the valuable roles of our patients and sponsors who are essential in influencing medical science.

We perform Phase I-IV clinical trials for multiple indications. Dr. Constantine Kotsanis oversees all trials as the Principal Investigator and has over 20 years of experience in clinical research. Dr. Kotsanis and Alinea Clinical Research staff share a passion to bring new and improved investigational drugs, therapies and devices to market. Our mission is to conduct our research with integrity, help our patients, and advance future medical care. 

We Are Dedicated to Improving Health Through Research

Benefits of Choosing Alinea



Each of our three sites are conveniently located just minutes from major highways and are within easy access of DFW International Airport.


  • Earn compensation
  • Receive free medical care
  • Have access to investigational medications
  • Contribute to innovations in medicine
  • Help many other people


  • Rapid start-up for any trials
  • Finalized contract/budget in 4-6 days
  • FDA-auditable source documents
  • Large conference area with WIFI
  • Eight exam rooms
  • Two dedicated lab rooms
  • 6 IV rooms
  • Secure drug storage
  • Knowledgeable in EDC and IVRS
  • Secure source document and CRF storage
  • Three storage areas, centrifuge, ambient storage, ECG, spirometry, scale and stadiometer, thermometers, sphygmomanometer, -20 degree freezer, refrigerator (2-8 degrees celsius)

Our Areas of Research Expertise


Alinea Clinical Research is an independent research company that serves diverse medical industries. We have completed studies for the nutritional, pharmaceutical, biotechnological and medical device industries and have conducted studies for these indications:


  • Allergies
  • Asthma/COPD
  • Autoimmune Diseases
  • Autism
  • Back Pain
  • Cardiovascular Disease
  • Cancer
  • C-Diff
  • Crohn’s Disease
  • Chronic Infection
  • Constipation
  • Dermatitis
  • Dyslipidemia
  • Fibromyalgia
  • GI Issues
  • Hot Flashes (Women)
  • Hypertension
  • Infant Formula
  • Irritable Bowel Syndrome
  • Lyme Disease
  • Migraines
  • Osteoarthritis, Knee/Hip
  • Pain
  • Tinea Pedis
  • Ulcerative Colitis

Download an Overview of Our Integrated Site

Alinea Site Overview Download (pdf)